4,4,4-Trinitrobutyric acid
Agent Name
4,4,4-Trinitrobutyric acid
CAS Number
5029-46-9
Formula
C4-H5-N3-O8
Major Category
Nitrogen Compounds
Synonyms
4,4,4-Trinitrobutanoic acid; BA 2759; Butyric acid, 4,4,4-trinitro-; gamma,gamma,gamma-Trinitrobutyric acid; Butanoic acid, 4,4,4-trinitro-; [ChemIDplus]
Category
Nitros, Aliphatic
Comments
Causes degenerative changes to brain, respiratory obstruction, and methemoglobinemia in oral lethal-dose studies of mice and rats; Causes changes in recordings from specific areas of the CNS, structural or functional changes in trachea or bronchi, and other liver changes in 26-week intermittent inhalation studies of rats; [RTECS] See "Butyric acid." See "Trinitromethane."
Biomedical References
Exposure Assessment
Lethal Concentration
LC (rat) > 30 mg/m3
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.