Agent Name
4-Isopropylaniline
Alternative Name
Cumidine
Major Category
Nitrogen Compounds
Synonyms
4-Amino-1-isopropylbenzene; 4-Aminocumene; Aniline, p-isopropyl-; beta-(4-Aminophenyl)propane; Cumene, p-amino-; p-Cumidine; p-Isopropylaniline; Benzenamine, 4-(1-methylethyl)-; Cumidine; [ChemIDplus] 4-(1-Methylethyl)benzenamine; [Merck Index] 1–Amino–4–isopropylbenzene; 1–Amino–4–isopropylbenzol; 4–Aminoisopropylbenzene; Aniline, 4–isopropyl; Benzolamin, 4–(1–methylethyl)–; p–Cumidin; p–Isopropylanilin; [IUCLID]
Category
Amines, Aromatic
Description
Liquid; [Merck Index] Clear dark red liquid; [Sigma-Aldrich MSDS]
Sources/Uses
Used in the determination of tungsten; [Merck Index] Used in chemical synthesis; [IUCLID] Used to make fine and large scale chemicals; [ECHA REACH Registrations]
Comments
Hematological changes (including increased methemoglobin), increased spleen and liver weights, and histopathological changes of the bone marrow, spleen, and liver observed in oral repeated dose/reproductive/developmental study of rats with NOEL for parental animals of 6 mg/kg/day; This study also demonstrated decreased pup body weights and viability on day 4 of lactation but no evidence of reproductive toxicity; [JECDB] May induce methemoglobinemia; [IUCLID] Causes burns; Toxic by ingestion, inhalation, and skin absorption; [ECHA REACH Registrations] A skin and strong eye irritant; May induce methemoglobinemia; [Sigma-Aldrich MSDS]
Methemoglobinemia
MetHgb is secondary toxic effect
Other Information
No other related information on this agent was found.