4-Isopropylaniline

Agent Name
4-Isopropylaniline
Alternative Name
Cumidine
CAS Number
99-88-7
Formula
C9-H13-N
Major Category
Nitrogen Compounds
4-Isopropylaniline formula graphical representation
Synonyms
4-Amino-1-isopropylbenzene; 4-Aminocumene; Aniline, p-isopropyl-; beta-(4-Aminophenyl)propane; Cumene, p-amino-; p-Cumidine; p-Isopropylaniline; Benzenamine, 4-(1-methylethyl)-; Cumidine; [ChemIDplus] 4-(1-Methylethyl)benzenamine; [Merck Index] 1–Amino–4–isopropylbenzene; 1–Amino–4–isopropylbenzol; 4–Aminoisopropylbenzene; Aniline, 4–isopropyl; Benzolamin, 4–(1–methylethyl)–; p–Cumidin; p–Isopropylanilin; [IUCLID]
Category
Amines, Aromatic
Description
Liquid; [Merck Index] Clear dark red liquid; [Sigma-Aldrich MSDS]
Sources/Uses
Used in the determination of tungsten; [Merck Index] Used in chemical synthesis; [IUCLID] Used to make fine and large scale chemicals; [ECHA REACH Registrations]
Comments
Hematological changes (including increased methemoglobin), increased spleen and liver weights, and histopathological changes of the bone marrow, spleen, and liver observed in oral repeated dose/reproductive/developmental study of rats with NOEL for parental animals of 6 mg/kg/day; This study also demonstrated decreased pup body weights and viability on day 4 of lactation but no evidence of reproductive toxicity; [JECDB] May induce methemoglobinemia; [IUCLID] Causes burns; Toxic by ingestion, inhalation, and skin absorption; [ECHA REACH Registrations] A skin and strong eye irritant; May induce methemoglobinemia; [Sigma-Aldrich MSDS]
Biomedical References

Exposure Assessment

Adverse Effects

Methemoglobinemia
MetHgb is secondary toxic effect
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.