alpha-Chloralose

Synonyms

(R)-1,2-O-(2,2,2-Trichloroethylidene)-alpha-D-glucofuranose; AGC; Alfamat; alpha-D-Glucochloralose; Alphachloralose; Alphakil; Anhydroglucochloral; Aphosal; Chloralosane; Chloralose; Chloralosum [INN-Latin]; Chloroalosane; Cloralosa [INN-Spanish]; Dorcalm; Dulcidor; Glucochloral [ISO-French]; Glucochloralose; Kalmettumsomniferum; Krakalos; Murex; Perglucorat; Somio; alpha-D-Glucofuranose, 1,2-O-((1R)-2,2,2-trichloroethylidene)-; alpha-D-Glucofuranose, 1,2-O-(2,2,2-trichloroethylidene)-, ®- (9CI); alpha-D-Glucofuranose, 1,2-O-(2,2,2-trichloroethylidene)-, (theta)-; [ChemIDplus] 1,2-O-[(1R)-2,2,2-Trichloroethylidene]-alpha-D-glucofuranose; [Merck Index]

Category

Rodenticides

Description

Solid; [Merck Index] White powder; [Alfa Aesar MSDS]

Sources/Uses

"A derivative of CHLORAL HYDRATE that was used as a sedative but has been replaced by safer and more effective drugs. Its most common use is as a general anesthetic in animal experiments." [ChemIDplus] Used as a rodenticide, to control avian pests, as a sedative, hypnotic, and surgical anesthetic for laboratory animals; [Merck Index] Registered in the EC for use as a rodenticide; [CPS&Q: Assessment Report] No active pesticide product registrations in the US; [NPIRS]

Comments

Chloral hydrate is one of the main metabolites; Not a skin or eye irritant or skin sensitizer; Causes CNS depression; Not a reproductive or developmental toxicant; No evidence of carcinogenicity; [ToxPlanet: CPS&Q: Assessment Report] An irritant; Toxic by ingestion; Harmful by inhalation; [Alfa Aesar MSDS] See "Chloral hydrate."

Biomedical References

2.81E-09 mm Hg

LC50 (rat) > 1,990 mg/m3

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)