Urethane

Agent Name
Urethane
Alternative Name
Carbamic acid, ethyl ester
CAS Number
51-79-6
Formula
C3-H7-N-O2
Major Category
Other Classes
Urethane formula graphical representation
Synonyms
Carbamic acid, ethyl ester; A 11032; Aethylcarbamat [German]; Aethylurethan [German]; Carbamidsaeure-aethylester [German]; Estane 5703; Ethyl carbamate; Ethyl urethan; Ethyl urethane; Ethylcarbamate; Ethylester kyseliny karbaminove [Czech]; Ethylurethan; Ethylurethane; Leucethane; O-Ethylurethane; Pracarbamin; Pracarbamine; U-Compound; Uretan etylowy [Polish]; Uretano [DCIT]; Urethan; Urethanum [INN-Latin]; X 41; Carbamic acid, ethyl ester; [ChemIDplus]
Category
Carbamic Acid Esters
Description
Water-soluble crystals or white powder; [CAMEO]
Sources/Uses
Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate; [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic; Occurs naturally in fermented wines and foods; [Merck Index]
Comments
Harmful by inhalation or skin absorption and toxic by ingestion; Toxic to the liver; May cause CNS depression; [CAMEO] Inhalation can cause unconsciousness; [ICSC] Induces genetic damage in germ cells of humans or animals (3A); [MAK]
Biomedical References

Exposure Assessment

Vapor Pressure
0.36 mm Hg
Explanatory Notes
mp = 118-122 deg F; bp = 360-363 deg F at 760 mm Hg; VP = 5.0 mm Hg at 150.4 deg F; [CAMEO] VP = 48 Pa (0.36 mm Hg) at 25 deg C; [ICSC]

Adverse Effects

Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes
IARC Carcinogen
Probable (2a)
NTP Carcinogen
Anticipated human carcinogen

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: