Bis(triphenylphosphine)nickel(II) chloride
Agent Name
Bis(triphenylphosphine)nickel(II) chloride
Formula
C36-H30-Cl2-Ni-P2
Synonyms
Bis(triphenylphosphine)dichloronickel; Bis(triphenylphosphine)nickel dichloride; Dichlorobis(triphenylphosphine)nickel; Nickel, bis(triphenylphosphine)dichloro-; Nickel, dichlorobis(triphenylphosphine)-; Phosphine, tributyl-, compd. with nickelchloride (2:1); [ChemIDplus]
Category
Metals, Organic Compounds
Description
Solid; [Sigma-Aldrich MSDS]
Sources/Uses
Used as a solvent in the production of active pharmaceutical ingredients (API); [ECHA REACH Registrations]
Comments
Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] May cause skin sensitization; [ECHA REACH Registrations] May cause skin sensitization; Possible carcinogen; [Sigma-Aldrich MSDS] See "Nickel" and linked occupational diseases.
PEL (OSHA)
1 mg/m3, as Ni
IARC Carcinogen
Established
NTP Carcinogen
Human carcinogen
Diseases
Occupational diseases associated with exposure to this agent: