Bis(triphenylphosphine)nickel(II) chloride

Agent Name
Bis(triphenylphosphine)nickel(II) chloride
CAS Number
14264-16-5
Formula
C36-H30-Cl2-Ni-P2
Major Category
Metals
Bis(triphenylphosphine)nickel(II) chloride formula graphical representation
Synonyms
Bis(triphenylphosphine)dichloronickel; Bis(triphenylphosphine)nickel dichloride; Dichlorobis(triphenylphosphine)nickel; Nickel, bis(triphenylphosphine)dichloro-; Nickel, dichlorobis(triphenylphosphine)-; Phosphine, tributyl-, compd. with nickelchloride (2:1); [ChemIDplus]
Category
Metals, Organic Compounds
Description
Solid; [Sigma-Aldrich MSDS]
Sources/Uses
Used as a solvent in the production of active pharmaceutical ingredients (API); [ECHA REACH Registrations]
Comments
Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] May cause skin sensitization; [ECHA REACH Registrations] May cause skin sensitization; Possible carcinogen; [Sigma-Aldrich MSDS] See "Nickel" and linked occupational diseases.
Biomedical References

Exposure Assessment

PEL (OSHA)
1 mg/m3, as Ni

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes
IARC Carcinogen
Established
NTP Carcinogen
Human carcinogen

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: