Dimethyltin dichloride

Synonyms

Cotin 210; Dichlorid dimethylcinicity [Czech]; Dichlorodimethylstannane; Dichlorodimethyltin; Dimethyldichlorostannane; Dimethyldichlorotin; Dimethyltindichloride; Dimethylzinndichloride [German]; Stannane, dichlorodimethyl-; Tin, dimethyl-, dichloride; [ChemIDplus] DMTC; [Shepard's Catalog of Teratogenic Agents] DMTCI; [OECD: SIDS Dossier] UN3146

Category

Tin Compounds, Organic

Description

Produced as a solid or aqueous solution; [ECHA - Proposal for Harmonised Classification and Labelling] White crystalline solid; [Alfa Aesar MSDS]

Sources/Uses

Used for stabilizing PVC potable water piping, making abrasion resistant glass containers, and as a catalyst for curing electrocoated paints; [Shepard's Catalog of Teratogenic Agents] Used to make other organotin compounds and for glass coating; [OECD: SIDS Dossier]

Comments

Produced as a mixture with monomethyltin trichloride (CAS# 993-16-8); Teratogenicity observed in rats administered 20 mg/kg on days 7-17 of gestation; [Shepard's Catalog of Teratogenic Agents] Corrosive to rabbit skin; The nervous system is the target of toxicity in 90-day oral studies of rats, with neuropathological lesions observed in one study at doses as low as 25 ppm (1.6/2.2 mg/kg/day); One oral study of rats produced serious teratogenic effects not considered as related to maternal toxicity; Another study of rats demonstrated no teratogenicity; Possible developmental neurotoxicity observed in other studies of rats; [ECHA - Proposal for Harmonised Classification and Labelling] Reacts with water; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Toxic by ingestion, inhalation, and skin absorption; [Alfa Aesar MSDS] See "Trimethyltin chloride" and "Di-n-butyltin dichloride." See "Tin, organic compounds."

Biomedical References

Yes

, as Sn

0.2 mg/m3, as Sn

0.1 mg/m3, as Sn

0.02 mg/m3, as Sn

25 mg/m3, as Sn

0.2 mm Hg

LC50 (rat) = 115 mg/m3/4hr

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organotin compound, solid, n.o.s."

Yes

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Skin burns

Processes

Industrial Processes with risk of exposure:

• Glass Manufacturing
• Painting (Pigments, Binders, and Biocides)