Mandelonitrile
Agent Name
Mandelonitrile
CAS Number
532-28-5
Formula
C8-H7-N-O
Major Category
Nitrogen Compounds
Synonyms
alpha-Hydroxybenzeneacetonitrile; Acetonitrile, hydroxyphenyl-; Amygdalonitrile; Benzaldehyde cyanohydrin; Benzaldehydkyanhydrin [Czech]; Glycolonitrile, phenyl-; Mandelic acid nitrile; Nitril kyseliny mandlove [Czech]; Phenylglycolonitrile; alpha-Hydroxybenzeneacetonitrile; Benzeneacetonitrile, alpha-hydroxy-; [ChemIDplus] alpha-Cyanobenzyl alcohol; alpha-Hydroxyphenylacetonitrile; Benzaldehyde, cyanohydrin; 2-Hydroxy-2-phenylacetonitrile; Hydroxyphenylacetonitrile; [CAMEO] UN3276
Category
Nitriles
Description
Reddish-brown liquid; [CAMEO] Yellow to red-brown liquid; [Alfa Aesar MSDS]
Sources/Uses
Used to make bitter almond water; [Merck Index] Used in organic synthesis; [NTP] "Mandelonitrile, with the formula C6H5CH(OH)CN, occurs in small amounts in the pits of some fruits. Related cyanogenic glycosides are known, such as amygdalin." [Wikipedia]
Comments
Mortality and corneal opacity observed immediately following application to the eye of a rabbit; [EPA - TSCATS] A severe eye irritant; Causes spastic paralysis and respiratory depression in subcutaneous lethal-dose studies of rabbits and frogs; Intravenous LD50 (mouse) = 5.6 mg/kg; [RTECS] An irritant that may cause serious eye injury; Toxic by ingestion; [Alfa Aesar MSDS] See "NITRILES." See "m-Phthalodinitrile."
Biomedical References
Exposure Assessment
TIH
Yes
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Nitriles, liquid, toxic, n.o.s."
Adverse Effects
Other Poison
Chemical Asphyxiant
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.