Methyl (E)-crotonate
Agent Name
Methyl (E)-crotonate
CAS Number
623-43-8
Formula
C5-H8-O2
Major Category
Other Classes
Synonyms
(E)-2-Butenoic acid methyl ester; (E)-Crotonic acid methyl ester; Methyl (E)-2-butenoate; Methyl E-crotonate; Methyl E-Propene-1-carboxylate; Methyl trans-2-butenoate; Methyl trans-crotonate; trans-2-Butenoic acid methyl ester; 2-Butenoic acid, methyl ester, (2E)-; 2-Butenoic acid, methyl ester, (E)-; Crotonic acid, methyl ester, (E)-; [ChemIDplus] UN3272
Category
Esters, Other
Description
Colorless liquid; [Alfa Aesar MSDS]
Comments
A moderate skin and mild eye irritant in rabbits; [ToxPlanet: EC: SCCNFP] Human volunteers tested with 6% in petrolatum demonstrated no irritation following 48-hour closed-patch test and sensitization reactions in 2 of 25 subjects; [EC: SCCNFP] Safe when used as a flavoring agent in food; [EFSA] A skin, respiratory tract, and strong eye irritant; [Alfa Aesar MSDS] Search for (623-43-8[EC/RN Number]) AND (allergic OR dermatitis OR sensitizer OR sensitization): no results; [PubMed]
Restricted
Prohibited for use as a fragrance due to sensitizing potential; [EC: SCCNFP]
Biomedical References
Exposure Assessment
Lethal Concentration
LC (rat) > 19,000 ppm/6hr
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Esters, n.o.s."
Adverse Effects
Skin Sensitizer
Yes
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: