m-Toluic acid
Agent Name
m-Toluic acid
CAS Number
99-04-7
Formula
C8-H8-O2
Major Category
Other Classes
Synonyms
3-Toluic acid; 3-Methylbenzoic acid; beta-Methylbenzoic acid; m-Methylbenzoic acid; m-Toluylic acid; meta-Toluic acid; Benzoic acid, 3-methyl-; [ChemIDplus] MTA; m-Methylbenzoate; [OECD SIDS: m-Toluic acid - 2003]
Category
Organic Acids
Description
White to yellowish or yellow solid with a sweet floral odor; [CAMEO] Light yellow powder; [Sigma-Aldrich MSDS]
Sources/Uses
Used primarily as an intermediate for the insect repellent DEET; About 1% used to make a plastic stabilizer; [OECD SIDS: m-Toluic acid - 2003]
Comments
Causes muscle weakness, respiratory depression, and nausea in oral lethal-dose studies of mice; [RTECS] Not considered a skin irritant; Potential sensitizer; Oral repeated dose study of rats produced changes in hematology and increased relative pituitary weight in males and increased relative and absolute liver weights (with corresponding histopathology) in females at 1,000 mg/mg/day (histological changes also observed in 300 mg/kg/day females); No evidence of reproductive or developmental toxicity; [OECD SIDS: m-Toluic acid - 2003] Harmful by ingestion; [Sigma-Aldrich MSDS] Search for (99-04-7[EC/RN Number]) AND (allergic OR dermatitis OR sensitizer OR sensitization): no results; [PubMed]
Biomedical References
Exposure Assessment
Vapor Pressure
0.00014 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.