N-Nitroso-2,6-dimethylmorpholine
Agent Name
N-Nitroso-2,6-dimethylmorpholine
CAS Number
1456-28-6
Formula
C6-H12-N2-O2
Major Category
Nitrogen Compounds
Synonyms
2,6-Dimethyl-N-nitroso-morpholine; 2,6-Dimethyl-N-nitrosomorpholine; 2,6-Dimethylnitrosomorpholine; Dimethylnitrosomorpholine; DMNM; Morpholine, 2,6-dimethyl-N-nitroso-; Nitroso-2,6-dimethylmorpholine; 2,6-Dimethyl-4-nitrosomorpholine; Morpholine, 2,6-dimethyl-4-nitroso-; [ChemIDplus]
Category
Nitrosamines
Sources/Uses
Formed from the nitrosation of 2,6-dimethylmorpholine (dehydration product of bis(2-hydroxypropyl)amine); Both can be found in industrial oils; Used in carcinogenesis research; [Cal/EPA: OEHHA]
Comments
Increases tumor incidence in experimental animals by various routes of exposure; [ToxPlanet: Cal/EPA: OEHHA] Causes other liver changes, chronic pulmonary edema, and ulceration of the stomach in oral lethal-dose studies of guinea pigs; [RTECS] See "Nitrosamines." See "N-Nitrosomorpholine."
Biomedical References
Exposure Assessment
Vapor Pressure
0.024 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.