Agent Name
Tetrabutyl pyrophosphate
Major Category
Pesticides
Synonyms
Butyl pyrophosphate; Diphosphoric acid, tetrabutyl ester; Pyrophosphoric acid, tetrabutyl ester; [ChemIDplus]
Category
Organophosphate Insecticides
Comments
Oral lethal-dose (rat) > 250 mg/kg; [RTECS] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs] See "Aspon," "TEPP," and "Sulfotepp."
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Other Poison
Organophosphate
Diseases
Occupational diseases associated with exposure to this agent: