Ranitidine

Synonyms

1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-; N-(2-((5-((Dimethylamino)methyl)furfuryl)thio)ethyl)-N'-methyl-2-nitro-1,1-ethenediamine; [ChemIDplus]

Category

Pharmaceuticals

Sources/Uses

"A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers." [ChemIDplus]

Comments

Ranitidine caused occupational asthma in a pharmacist packaging the material in a pharmaceutical company. Specific IgE was not done. Broncho-provocation testing was positive. [Reference #1] Ranitidine can cause allergic contact dermatitis. [Kanerva, p. 481]

Reference Link #1

Biomedical References

Yes

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic