Dimethenamid-P
Agent Name
Dimethenamid-P
CAS Number
163515-14-8
Formula
C12H18ClNO2S
Major Category
Pesticides
Synonyms
2-chloro-N-(2,4-dimethylthiophen-3-yl)-N-[(2S)-1-methoxypropan-2-yl]acetamide; [PubChem] S-Dimethamid; Outlook herbicide; Tower herbicide; [ACGIH TLVs and BEIs]
Category
Herbicides, Other
Description
Yellow to dark-brown liquid with a faintly aromatic odor; [ACGIH TLVs and BEIs]
Sources/Uses
Manufacturing and field application (early post-emergent herbicide against annual grasses and some broad leaf weeds; [ACGIH TLVs and BEIs]
Comments
TLV Basis = Liver damage; bile duct hyperplasia in the absence of reliable human data; NOAELs = <2.1 mg/kg in 1-year feeding study in dogs; Rats less sensitive with NOAEL of <6.8 mg/kg in a 2- year feeding study; "A DSEN notation is recommended based on the positive response elicited in the guinea pig." [ACGIH TLVs and BEIs]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
No
Vapor Pressure
1.8E-05 mm Hg
Explanatory Notes
See 2024 "Notice of Intended Changes" for TLV; [ACGIH TLVs and BEIs]
Adverse Effects
Skin Sensitizer
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
ACGIH Carcinogen
Confirmed Animal
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: