Sevoflurane

Agent Name
Sevoflurane
CAS Number
28523-86-6
Formula
C4H3F7O
Major Category
Other Uses
Sevoflurane formula graphical representation
Synonyms
Ultane;1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane; Sevofluran; [PubChem] Sojourn; Sevorane; Piramal; [ACGIH TLVs and BEIs]
Category
Waste Anesthetic Gases
Description
A clear, nonflammable colorless liquid with a non-irritating odor; [ACGIH TLVs and BEIs]
Sources/Uses
Used as an inhalation anesthetic; [ACGIH TLVs and BEIs]
Comments
TLV Basis = CNS impairment; Human data demonstrates sedation starting at 2,000 ppm. "Epidemiologic studies provide inconsistent evidence regarding the role of sevoflurane in adverse health effects, including spontaneous abortion, congenital abnormalities, kidney and liver damage, genotoxicity, and developmental neurotoxicity." [ACGIH TLVs and BEIs]
Biomedical References
Search PubMed

Exposure Assessment

Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
50 ppm
Vapor Pressure
157 mm Hg

Adverse Effects

Neurotoxin
Acute solvent syndrome

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: