Diisopropylamine

Agent Name
Diisopropylamine
CAS Number
108-18-9
Formula
C6-H15-N
Major Category
Nitrogen Compounds
Diisopropylamine formula graphical representation
Synonyms
2-Propanamine, N-(1-methylethyl)-; N-(1-Methylethyl)-2-propanamine; N-Isopropyl-1-amino-2-methylethane; [ChemIDplus] UN1158
Category
Amines, Aliphatic
Description
Colorless liquid with an ammonia- or fish-like odor; [NIOSH]
Sources/Uses
Used as a catalyst and chemical intermediate; [ACGIH] Many aliphatic amines are used as curing agents for epoxy resins. [Sullivan, p. 473]
Comments
Liquid causes first degree burns on short exposure; [CHRIS] Corrosive to skin; [Quick CPC] Diisopropylamine is a severe pulmonary irritant in acute and chronic animal studies. At concentrations of 25 to 50 ppm, workers have experienced transient corneal injury, nausea, and headache. [ACGIH] A corrosive substance that causes lacrimation and may cause lung edema after inhalation of high concentrations; [ICSC]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
5 ppm
PEL (OSHA)
5 ppm
IDLH (NIOSH)
200 ppm
Excerpts from Documentation for IDLHs
Human data: Complaints of nausea, headache, and temporary dimness in vision were reported in workers 2 to 3 hours following several 5­ to 10­minute exposures to about 176 ppm; concentrations otherwise during the workshift averaged about 24 to 48 ppm [Treon et al. 1949].
Vapor Pressure
79.4 mm Hg
Odor Threshold Low
0.13 ppm
Lethal Concentration
LC50 (rat) = 4,800 mg/m3/2h
Explanatory Notes
Detection odor threshold from AIHA (mean = 0.13 ppm); Flash point = -1 deg C; VP from HSDB;
Reference Link #2
NFPA
may ignite at ambient temp

Adverse Effects

Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: