Azinphos-methyl

Synonyms

Guthion; 1,2,3-Benzotriazin-4(3H)-one, 3-(mercaptomethyl)-, O,O-dimethyl phosphorodithioate; 3-(Mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one O,O-dimethyl phosphorodithioate S-ester; 3-Dimethoxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one; Azinfos-methyl [Dutch]; Azinphos; Azinphos methyl; Azinphos-metile [Italian]; BAY 17147; BAY 9027; Bayer 17147; Bayer 9027; Benzotriazine derivative of a methyl dithiophosphate; Benzotriazinedithiophosphoric acid dimethoxy ester; Carfene; Cotneon; Cotnion; Cotnion methyl; Crysthion 2L; Crysthyon; Dimethyldithiophosphoric acid N-methylbenzazimide ester; EPA Shaughnessy #058001; Gusathion; Gusathion 25; Gusathion K; Gusathion M; Gusathion methyl; Gusathion-20; Guthion; Metazintox; Methyl guthion; Methylazinphos; Methylgusathion; Metiltriazotion; N-Methylbenzazimide, dimethyldithiophosphoric acid ester; O,O-Dimethyl S-(3,4-dihydro-4-keto-1,2,3-benzotriazinyl-3-methyl) dithiophosphate; O,O-Dimethyl S-(4-oxo-1,2,3-benzotriazino(3)-methyl) thiothionophosphate; O,O-Dimethyl S-(4-oxo-1,2,3-benzotriazino(3)-methyl)thiothionophosphate; O,O-Dimethyl S-(4-oxo-3H-1,2,3-benzotriazine-3-methyl)phosphorodithioate; O,O-Dimethyl S-(4-oxobenzotriazino-3-methyl)phosphorodithioate; O,O-Dimethyl S-4-oxo-1,2,3-benzotriazin-3(4H)-ylmethyl phosphorodithioate; O,O-Dimethyl phosphorodithioate S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one (8CI); O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiofosfaat [Dutch]; O,O-Dimethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiophosphat [German]; O,O-Dimethyl-S-(1,2,3-benzotriazinyl-4-keto)methyl phosphorodithioate; O,O-Dimethyl-S-(4-oxobenzotriazin-3-methyl)-dithiophosphat [German]; O,O-Dimethyl-S-(benzaziminomethyl) dithiophosphate; O,O-Dimetil-S-((4-oxo-3H-1,2,3-benzotriazin-3-il)-metil)-ditiofosfato [Italian]; Phosphorodithioic acid, O,O-dimethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester; Phosphorodithioic acid, O,O-dimethyl ester, S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one; R 1582; S-(3,4-Dihydro-4-oxo-benzo(alpha)(1,2,3)triazin-3-ylmethyl) O,O-dimethyl phosphorodithioate; S-3,4-Dihydro-4-oxobenzo(d)(1,2,3)triazin-3-ylmethyl O,O-dimethyl phosphorodithioate; [ChemIDplus]

Category

Organophosphate Insecticides

Description

Colorless crystals or a brown, waxy solid. [insecticide]; [NIOSH]

Sources/Uses

Used primarily to kill leaf feeding insects; [EXTOXNET] Used to control insects on fruits, melons, nuts, vegetables, field crops, ornamentals, and shade trees; [ACGIH]

Comments

It is classified as "highly toxic"; the EPA reentry interval is 24 hours; [EXTOXNET] A dermal sensitizer based on positive animal testing (maximization and patch testing); [ACGIH] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

Reference Link #1

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Yes

0.2 mg/m3, inhalable fraction and vapor

0.2 mg/m3

1 mg/m3, inhalable fraction

10 mg/m3

8E-09 mm Hg

Reference Link #2

Yes

Not Classifiable

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic
• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)