1,1,2,3-Tetrachloropropene
Agent Name
1,1,2,3-Tetrachloropropene
CAS Number
10436-39-2
Formula
C3-H2-Cl4
Major Category
Other Classes
Synonyms
1-Propene, 1,1,2,3-tetrachloro-; Propene, 1,1,2,3-tetrachloro-; [ChemIDplus] TCPP; [IUCLID] TCP; Tetrachloropropene; [EPA - TSCATS]
Category
Halogenated Aliphatics, Unsaturated
Description
Liquid; [IUCLID]
Comments
No significant adverse effects observed in 13 week inhalation study with rats; No significant adverse effects observed in reproductive inhalation study with rats; Necrotic lesions of the liver were observed in rats at gavage doses of 300 mg/kg for one month; Effects in dermal LD50 study with rabbits include skin necrosis followed by eschar formation and exfoliation; Severely irritating to skin (superficial necrosis) and moderately irritating to eyes (with conjunctival redness, chemosis, and discharge) of rabbits; All eye irritation reversed within 7 days; [HSDB]
Biomedical References
Exposure Assessment
Vapor Pressure
2.67 mm Hg
Lethal Concentration
LC50 (rat) = 1,500 mg/m3
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.