1,2,3-Trichloropropene

Synonyms

1,2,3-Trichlor-1-propene; 1,2,3-Trichloro-1-propene; 1-Propene, 1,2,3-trichloro-; 2,3-Dichloroallyl chloride; Propene, 1,2,3-trichloro-; [ChemIDplus]

Category

Halogenated Aliphatics, Unsaturated

Description

Amber liquid; [CAMEO]

Sources/Uses

Used as a chemical intermediate; [HSDB]

Comments

Caused somnolence in rats at 36 ppm for 6 hours; [RTECS] External application to rabbit eyes scored 5 on a scale of 1-10 after 24 hours (moderate irritation); Observations in three month rodent inhalation study include eye and upper respiratory tract irritation and increased liver enzymes; No significant gross or histopathological effects observed in 13 week inhalation study with rats; A ten week inhalation study with rats produced no evidence of reproductive or developmental toxicity; [HSDB] May cause irritation or burns; [CAMEO] An irritant that may cause burns; [MSDSonline]

Biomedical References

4.4 mm Hg

LCLo (rat) = 500 ppm/4h

Explanatory Notes

Flash point = 85 deg C; [HSDB] VP from ChemIDplus;

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect