1,2-Dibromopropane
Agent Name
1,2-Dibromopropane
CAS Number
78-75-1
Formula
C3-H6-Br2
Major Category
Other Classes
Synonyms
2,3-Dibromopropane; Propylene dibromide; Propane, 1,2-dibromo-; [ChemIDplus]
Category
Halogenated Aliphatics, Saturated
Description
Colorless liquid; [Merck Index]
Sources/Uses
Used as a research chemical; [HSDB]
Comments
Increased liver enzymes in feeding studies of mice; Some evidence of mutagenicity; Emergency medical treatment: see "2-Bromopropane." [HSDB] High concentrations may have irritating and narcotic effects; [CAMEO] A mutagen; Effects in high-dose animal studies include fatty liver degeneration and acute renal failure; [RTECS]
Biomedical References
Exposure Assessment
Vapor Pressure
7.84 mm Hg
Lethal Concentration
LC50 (rat) = 12,000 mg/m3/4h
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: