1,3-Diamino-2-thiourea
Agent Name
1,3-Diamino-2-thiourea
Alternative Name
Thiocarbazide
CAS Number
2231-57-4
Formula
C-H6-N4-S
Major Category
Nitrogen Compounds
Synonyms
Thiocarbazide; Thiocarbohydrazide; Carbohydrazide, thio-; Carbonothioic dihydrazide; Hydrazinecarbohydrazonothioic acid; Hydrazinecarbohydrazonothioic acid (VAN); TCH; Thiocarbazide; Thiocarbonic dihydrazide; Thiocarbonohydrazide; [ChemIDplus]
Category
Thiourea Compounds
Description
Solid; [CAMEO] White powder; [Alfa Aesar MSDS]
Sources/Uses
Used in electron microscopy to deposit electron-opaque material for ultrastructural analysis and as a veterinary medication; [HSDB] Used to make pesticides and other agricultural chemicals; [EPA]
Comments
Emergency treatment: "Thiocarbazide"; Causes seizures in animal experiments; No reports of human poisoning cases; [HSDB] Not irritating to rabbit skin or eyes; Muscle spasms observed in lethal-dose studies of rats (oral and inhalation); Causes gene mutations in bacteria and unscheduled DNA synthesis in vitro; [EPA ChAMP] A mild eye irritant; Causes convulsions, somnolence, and dyspnea in oral lethal-dose studies of rats, guinea pigs, and mice; [RTECS] An irritant; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Lethal Concentration
LC50 (rat) = 50 mg/m3/4h
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.