1,3-Dichloro-2-butene

Synonyms

1,3-Dichlorobutylene; 2-Butene, 1,3-dichloro-; [ChemIDplus] 1,3-DCB; [SIDS UNEP]

Category

Halogenated Aliphatics, Unsaturated

Description

Clear to straw-colored liquid; [HSDB] Colorless liquid; [MSDSonline]

Sources/Uses

Used in the pesticide DDB and as an intermediate in organic synthesis; [HSDB] Commercially manufactured and consumed solely as on-site intermediate in the production of 2,3-dichloro-1,3-butadiene (comonomer for polychloroprene synthetic rubber); [SIDS UNEP]

Comments

A skin, eye, and respiratory tract irritant; Exposure to high vapor concentrations can cause severe respiratory distress, lacrimation, and possibly coma; Inhalation of low concentrations may cause CNS depression; May cause kidney, liver, and heart injury; Emergency medical treatment: "chlorinated hydrocarbon insecticides"; [HSDB] Corrosive to rabbit skin; Occupational exposures demonstrate irritation and corrosive injuries to skin, with the vapor causes eye and respiratory tract irritation; A possible carcinogen based on the structural analog 1,3-Dichloropropene (DCP) CAS # 542-75-6, which has an IARC classification of “possible human carcinogen”; No evidence of reproductive or developmental toxicity in rats or rabbits; [SIDS UNEP]

Biomedical References

12.6 mm Hg

LC50 (rat) = 3,930 mg/m3/4h

Explanatory Notes

Flash point = 27 deg C; [HSDB] VP from ChemIDplus;

may ignite at ambient temp

Yes

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)