1,4-Dithiane
Agent Name
1,4-Dithiane
CAS Number
505-29-3
Formula
C4-H8-S2
Major Category
Other Classes
Synonyms
1,4-Dithiacyclohexane; 1,4-Dithiin, tetrahydro-; Diethylene disulfide; p-Dithiin, tetrahydro-; p-Dithane; p-Dithiane; [ChemIDplus]
Category
Sulfur Compounds
Description
White solid; [HSDB] White solid with a strong offensive odor; [Alfa Aesar MSDS]
Sources/Uses
Associated with production and storage of munitions; [ChemIDplus] Used in organic synthesis; [HSDB] Used as flavoring agent; [JECFA]
Comments
A contaminant of mustard gas; Occupational exposure may occur where mustard gas has been used or stored; Causes ataxia, lacrimation, and crusts on eyes and nose in acute lethal studies of rats; Anatomic changes to nose, liver, and kidneys observed in 90-day gavage study of rats; [HSDB] Safe when used as a flavoring agent in food; [JECFA] Causes changes in bladder and spleen weight in 90-day intermittent oral studies of rats; [RTECS]
Biomedical References
Exposure Assessment
Vapor Pressure
1.57 mm Hg
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.