Agent Name
1'-Hydroxysafrole
Major Category
Other Classes
Synonyms
1,2-Methylenedioxy-4-(1-hydroxyallyl)benzene; 1,3-Benzodioxole-5-(2-propen-1-ol); 1,3-Benzodioxole-5-methanol, alpha-ethenyl-; Piperonyl alcohol, alpha-vinyl-; alpha-Ethenyl-1,3-benzodioxole-5-methanol; [ChemIDplus]
Category
Other Aromatic Compounds
Comments
A mutagen and tumorigen; [RTECS] Emergency treatment: "Sassafras oil"; Safrole is the toxic agent in sassafras oil; Safrole is classified as 2B (possible human carcinogen) by IARC; Safrole is metabolized in the body to 1'-hydroxysafrole; Ingestion of 5 ml of sassafras oil can cause severe symptoms (tachycardia, hypotension, and respiratory paralysis) or death; Large doses may damage the liver; Drinking 10 cups of sassafras tea caused sweating in one adult subject; [HSDB] See "Safrole."
Vapor Pressure
7.78E-05 mm Hg
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Other Information
No other related information on this agent was found.