1'-Hydroxysafrole
Agent Name
1'-Hydroxysafrole
CAS Number
5208-87-7
Formula
C10-H10-O3
Major Category
Other Classes
Synonyms
1,2-Methylenedioxy-4-(1-hydroxyallyl)benzene; 1,3-Benzodioxole-5-(2-propen-1-ol); 1,3-Benzodioxole-5-methanol, alpha-ethenyl-; Piperonyl alcohol, alpha-vinyl-; alpha-Ethenyl-1,3-benzodioxole-5-methanol; [ChemIDplus]
Category
Other Aromatic Compounds
Comments
A mutagen and tumorigen; [RTECS] Emergency treatment: "Sassafras oil"; Safrole is the toxic agent in sassafras oil; Safrole is classified as 2B (possible human carcinogen) by IARC; Safrole is metabolized in the body to 1'-hydroxysafrole; Ingestion of 5 ml of sassafras oil can cause severe symptoms (tachycardia, hypotension, and respiratory paralysis) or death; Large doses may damage the liver; Drinking 10 cups of sassafras tea caused sweating in one adult subject; [HSDB] See "Safrole."
Biomedical References
Exposure Assessment
Vapor Pressure
7.78E-05 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.