1-Amino-2-methylanthraquinone

Agent Name
1-Amino-2-methylanthraquinone
Alternative Name
Disperse Orange 11
CAS Number
82-28-0
Formula
C15-H11-N-O2
Major Category
Dyes
1-Amino-2-methylanthraquinone formula graphical representation
Synonyms
Disperse Orange 11; 1-Amino-2-methyl-9,10-anthracenedione; 1-Amino-2-methyl-9,10-anthraquinone; 2-Methyl-1-anthraquinonylamine; 9,10-Anthracenedione, 1-amino-2-methyl-; Acetate Fast Orange R; Acetoquinone Light Orange JL; Anthraquinone, 1-amino-2-methyl-; Artisil Orange 3RP; C.I. 60700; C.I. Disperse Orange 11; CI 60700; CI Disperse Orange 11; Celliton Orange R; Cilla Orange R; Disperse Orange; Disperse Orange (VAN); Disperse Orange (anthraquinone dye); Disperse Orange 11; Duranol Orange G; Microsetile Orange RA; Nyloquinone Orange JR; Oranz disperzni 11 [Czech]; Perliton Orange 3R; Serisol Orange YL; Supracet Orange R; [ChemIDplus]
Category
Anthraquinone Dyes
Description
Orange to dark red solid; [HSDB] Red solid; [CAMEO]
Sources/Uses
Used as a chemical intermediate for dyes and to dye synthetic fibers, furs, and thermoplastic resins; Not produced in the US; [HSDB] As of 1998, was being commercially manufactured in Western Europe; [IARC] US production ceased in 1970, with the last reported import in 1972; [NTP]
Comments
Evidence for carcinogenicity in laboratory animals include carcinomas in the liver and kidney; Shown to be mutagenic; Emergency treatment: "Anthraquinones"; Anthraquinones have cathartic action after ingestion, and in severe cases, may cause kidney damage, liver enzyme elevation, GI hemorrhage, seizures, and coma; [HSDB] May cause skin and eye irritation, methemoglobinemia, and liver injury; [CAMEO] An irritant; Harmful if ingested, inhaled, or absorbed through the skin; Target organs or liver and kidneys; [Aldrich MSDS]
Biomedical References

Exposure Assessment

Vapor Pressure
3.82E-08 mm Hg

Adverse Effects

Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
NTP Carcinogen
Anticipated human carcinogen

Diseases, Processes, and Activities Linked to This Agent