Thiosemicarbazide
Agent Name
Thiosemicarbazide
Alternative Name
1-Amino-2-thiourea
CAS Number
79-19-6
Formula
C-H5-N3-S
Major Category
Nitrogen Compounds
Synonyms
1-Amino-2-thiourea; 1-Aminothiourea; 2-Thiosemicarbazide; 3-Thiosemicarbazide; Aminothio-urea; Hydrazinecarbothioamide; Isothiosemicarbazide; Isothiosemicarbazide (VAN); N-Aminothiourea; Semicarbazide, 3-thio-; Semicarbazide, thio-; TSC; TSZ; Thiocarbamoylhydrazine; Thiocarbamylhydrazine; [ChemIDplus] UN2811
Category
Thiourea Compounds
Description
White, odorless solid; [Hawley] Off-white crystalline powder; [Alfa Aesar MSDS]
Sources/Uses
Used as a reagent for ketones and detection of metals, rodenticide, and chemical intermediate; Also used in photography; [HSDB] Effective for controlling bacterial leaf blight in rice: [CAMEO]
Comments
May cause irritation, goiter, bone marrow depression, hyperglycemia, CNS excitation, seizures, and pulmonary edema after ingestion; A GABA synthesis inhibitor in experimental animals; [HSDB] Causes convulsions in lethal-dose studies of guinea pigs, mice, and cats (oral, ocular, intravenous, and intraperitoneal routes); [RTECS] An irritant; [Alfa Aesar MSDS]
Restricted
Not registered as a pesticide for use in the US; [CAMEO]
Biomedical References
Exposure Assessment
Vapor Pressure
0.33 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s." VP from ChemIDplus;
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: