1-Aziridineethanol
Agent Name
1-Aziridineethanol
CAS Number
1072-52-2
Formula
C4-H9-N-O
Major Category
Nitrogen Compounds
Synonyms
1-(2-Hydroxyethyl)ethylenimine; 1-Azirdineethanol; 2-(1-Aziridinyl)ethanol; 2-Hydroxy-1-ethylaziridine; Ethanol, 2-(1-aziridinyl)-; Hydroxyethylethyleneimine; N-(2-Hydroxyethyl)aziridine; N-(2-Hydroxyethyl)ethyleneimine; N-(2-Hydroxyethyl)ethylenimine; N-(Hydroxyethyl)ethyleneimine; N-(beta-Hydroxyethyl)aziridine; N-Hydroxyethyl ethylene imine; beta-Hydroxy-1-ethylaziridine; [ChemIDplus]
Category
Other Nitrogen Compounds
Description
Colorless liquid; [Hawley] Colorless or yellow liquid; [CAMEO]
Sources/Uses
Used as a chemical intermediate and chemical modifier for latex polymers, coatings, textile resins, starches, paper, wood, and cellulose fibers; [HSDB]
Comments
Single oral doses (125-1000 mg/kg) to rats caused liver necrosis; [HSDB] Hydrolyzes forming diethanolamine; A skin, eye, nose and mucous membrane irritant; May cause liver injury; [CAMEO] Caused severe irritation to eyes and skin of rabbits; [RTECS] Causes burns; Highly toxic through skin absorption; An upper respiratory tract irritant; Toxic if swallowed; [Aldrich MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.49 mm Hg
Lethal Concentration
LC (rat) > 850 ppm/8h
Explanatory Notes
Flash point = 85 deg C; [Hawley]
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns
IARC Carcinogen
Not classifiable
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: