1-Bromobutane
Agent Name
1-Bromobutane
Alternative Name
n-Butyl bromide
CAS Number
109-65-9
Formula
C4-H9-Br
Major Category
Other Classes
Synonyms
1-Butyl bromide; Butyl bromide; Butane, 1-bromo-; n-Butyl bromide; [ChemIDplus] UN1126
Category
Halogenated Aliphatics, Saturated
Description
Colorless to pale straw-colored liquid; [HSDB] Colorless liquid; [MSDSonline]
Sources/Uses
Used as an alkylating agent and in the preparation of drugs; [HSDB]
Comments
Flammable liquid; [Hawley] Irritating to the skin of mice and the eyes of rabbits; Did not induce sensitization by application to the ear of mice and determined by local lymph node assay; Degeneration of vacuolar liver cells was observed in 28 day feeding study with rats; Evidence of mutagenicity in Salmonella typhimurium and Chinese hamster cells; [HSDB] A skin, eye, nose, throat, and respiratory tract irritant; [CAMEO] Causes somnolence and ataxia in lethal-dose feeding studies of rats; [RTECS]
Biomedical References
Exposure Assessment
Vapor Pressure
42 mm Hg
Lethal Concentration
LC50 (rat) = 47,000 mg/m3/2h
Explanatory Notes
Flash point = 18 deg C; [HSDB] VP from ChemIDplus;
NFPA
may ignite at ambient temp
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: