1-Chloropropane
Agent Name
1-Chloropropane
Alternative Name
Propyl chloride
CAS Number
540-54-5
Formula
C3-H7-Cl
Major Category
Other Classes
Synonyms
n-Propyl chloride; Propane, 1-chloro-; Propyl chloride; [ChemIDplus] UN1278
Category
Halogenated Aliphatics, Saturated
Description
Colorless liquid; [Merck Index]
Sources/Uses
Used as a chemical intermediate for n-Propylamine; Has been studied for use as an anesthetic and parasiticidal drug; [HSDB]
Comments
Flammable liquid; [Hawley] Irritant and CNS depressant; External application to rabbit eyes scored 2 on a scale of 1-10 (10 being most severe) for degree of injury after 24 hours; Observations in 4-day inhalation study with rats include minor alveolar hemorrhage and focal necrosis of the liver; Emergency medical treatment: see "Ethyl chloride." [HSDB] An eye, nose, and throat irritant; May cause CNS depression in high concentrations; [CAMEO]
Restricted
No known current commercial production in the US; [HSDB]
Biomedical References
Exposure Assessment
Vapor Pressure
345 mm Hg
Explanatory Notes
Flash point = -17.7 deg C; [Hawley] VP from ChemIDplus;
NFPA
may ignite at ambient temp
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: