2,5-Dinitrophenol
Agent Name
2,5-Dinitrophenol
CAS Number
329-71-5
Formula
C6-H4-N2-O5
Major Category
Nitrogen Compounds
Synonyms
2,5-DNP; 2,5-Dinitrofenol [Czech]; Phenol, 2,5-dinitro-; Phenol, gamma-dinitro-; gamma-Dinitrophenol; [ChemIDplus] UN1320; UN0076
Category
Nitrophenols
Description
Yellow solid; [Merck Index] Light yellow crystals; [MSDSonline]
Sources/Uses
Used as an indicator and to make dyes and other organic chemicals; [Merck Index]
Comments
Causes first degree burns after brief exposure; [CHRIS] Emergency treatment: see "Dinitrophenol." A mucous membrane irritant; Can induce methemoglobinemia; [HSDB] Toxic by inhalation, ingestion, and skin contact; [eChemPortal: ESIS] An irritant; Readily absorbed through skin; May cause liver damage; Disrupts oxidative phosphorylation; [MSDSonline] See "Dinitrophenol."
Biomedical References
Exposure Assessment
Vapor Pressure
0.000122 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Dinitrophenol, wetted with not less than 15% water, by weight".
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Dermatotoxin
Skin burns
Other Poison
Uncoupler
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: