2,6-Diethylaniline
Agent Name
2,6-Diethylaniline
CAS Number
579-66-8
Formula
C10-H15-N
Major Category
Nitrogen Compounds
Synonyms
2,6-Diethyl aniline; 2,6-Diethylbenzenamine; Aniline, 2,6-diethyl-; Benzenamine, 2,6-diethyl-; [ChemIDplus]
Category
Amines, Aromatic
Description
Yellow liquid; [HSDB] Colorless liquid; [MSDSonline]
Sources/Uses
Used to make pesticides, triazine herbicides, dyestuffs, antioxidants, pharmaceuticals, synthetic resins, fragrances, and other products; Also found in soil as microbial metabolite of some acetanilide herbicides, including alachlor; [HSDB]
Comments
Emergency treatment: Methemoglobinemia; [HSDB] Cyanosis observed in oral lethal-dose study of rats; No significant pathological changes observed; Effects in lethal-concentration inhalation study with rats include bronchial pneumonia, hemorrhage and edema of the lungs, congestion and focal necrosis of the liver, and cloudy swelling in the kidneys; No adverse changes in blood or clinical chemistries, or gross or histopathological examinations observed in 90-day inhalation study of rats; Histopathological changes of liver in other high-dose studies with rats and dogs; Teratogenic effects (decrease in fetal weight and retarded ossification) observed in gavage study with rats at doses maternally toxic; Irritating to rabbit eyes, but not to skin; Not sensitizing or irritating to guinea pig skin; [EPA HPVIS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.00383 mm Hg
Lethal Concentration
LC50 (rat) = 4,700 mg/m3/6h
Explanatory Notes
VP from ChemIDplus;
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.