2-Aminoanthraquinone
Agent Name
2-Aminoanthraquinone
CAS Number
117-79-3
Formula
C14-H9-N-O2
Major Category
Dyes
Synonyms
2-Amino-9,10-anthracenedione; 2-Amino-9,10-anthraquinone; 9,10-Anthracenedione, 2-amino-; Aminoanthraquinone; beta-Anthraquinonylamine; [ChemIDplus]
Category
Anthraquinone Dyes
Description
Red or orange-brown solid; [HSDB] Orange-brown powder; [MSDSonline]
Sources/Uses
Used as an intermediate for dyes and pharmaceuticals; [HSDB]
Comments
No listed effects of short-term or long-term exposure; [ICSC] Evidence for carcinogenicity (hepatocellular neoplasms and carcinomas) in rats and mice; Effects to female rats in sub-chronic and chronic feeding studies include nephrotoxicity and decreased hemoglobin; Emergency treatment: "Anthraquinones"; Anthraquinones have cathartic action after ingestion, and in severe cases, may cause kidney damage, liver enzyme elevation, GI hemorrhage, seizures, and coma; [HSDB] May cause irritation and be absorbed through skin; Carcinogenic to animals; [CAMEO] Not irritating to skin or eyes of rabbits; Evidence for mutagenicity includes positive results in six of seven Ames Tests using various strains of Salmonella typhimurium, two cytogenic assays, four mouse lymphoma assays, and three in-vitro micronucleus assays; [IUCLID]
Biomedical References
Exposure Assessment
Vapor Pressure
5E-11 mm Hg
Explanatory Notes
Flash point = 283 deg C; [ICSC]
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.