2-Chloro-1,1,1,2-tetrafluoroethane

Synonyms

1,1,1,2-Tetrafluoro-2-chloroethane; 1,1,1,2-Tetrafluorochloroethane; 1-Chloro-1,2,2,2-tetrafluoroethane; Freon 124; HCFC 124; Hfa-124; R 124; Ethane, 2-chloro-1,1,1,2-tetrafluoro-; Chlorotetrafluoroethane; [ChemIDplus] UN1021

Category

Chlorofluorocarbons

Description

A colorless gas with a faint ethereal odor at room temperature and atmospheric pressure; Colorless liquid under pressurized conditions; [eChemPortal: SIDSUNEP] Colorless volatile liquid; Faint sweetish odor; Gas at ambient temperatures; [MSDSonline]

Sources/Uses

Used as a foam blowing agent and refrigerant; [eChemPortal: SIDSUNEP]

Comments

Evaporating liquid can cause frostbite; [CHEMINFO] Can cause anesthesia and sensitize the heart to catecholamines; May cause liver injury; Vapors are heavier than air and can accumulate in low-lying areas; [HSDB] In confined space spill, may displace air and act as simple asphyxiant; Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; A severe eye irritant; [MSDSonline] 25,000 ppm is the threshold for cardiac sensitization in dogs; [AIHA]

Biomedical References

LC50 (rat) > 360,000 ppm/6H;

Explanatory Notes

Boiling point = -12 deg C; [HSDB]

1,000 ppm

5,000 ppm

10,000 ppm

1000 ppm

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Poison

Simple Asphyxiant

Diseases

Occupational diseases associated with exposure to this agent:

• Asphyxiation, simple
• Solvents, acute toxic effect