2-Chlorophenol
Agent Name
2-Chlorophenol
CAS Number
95-57-8
Formula
C6-H5-Cl-O
Major Category
Other Classes
Synonyms
2-Chloro-1-hydroxybenzene; 2-Hydroxychlorobenzene; o-Chlorophenic acid; o-Chlorophenol; o-Chlorphenol [German]; p-Chlorfenol [Czech]; Pine-O Disinfectant; Septi-Kleen; Phenol, 2-chloro-; Phenol, o-chloro-; [ChemIDplus] CHLORO-2 PHENOL; OCP; Ortho chlorophenol; ORTHOMONOCHLOROPHENOL; [IUCLID] UN2021
Category
Chlorophenols
Description
Colorless to yellow-brown liquid with an unpleasant odor; [Hawley] Sensitive to light and moisture; [CHEMINFO] Faintly yellow clear liquid with a stench; [Sigma-Aldrich MSDS]
Sources/Uses
Used in the production of higher chlorinated phenols, catechol, profenofos, dyestuffs, and preservatives; Also used to extract sulfur and nitrogen compounds from coal and as a soil sterilant, disinfectant, antiseptic, and phenolic resin comonomer; [HSDB] Used as a polymer intermediate for fire-retardant varnishes and as a cotton fabric treatment to provide rot resistance; [INCHEM] Found in textile samples of cotton and wool; Used to protect textiles during transport and storage; [ExPub: Danish Ministry of the Environment]
Comments
A severe skin, eye, and respiratory tract irritant; May cause pulmonary edema; Inhalation may cause CNS effects; [ICSC] May be fatal by inhalation, ingestion, and skin absorption; [CAMEO] Corrosive to skin and eyes based on animal studies; [CHEMINFO] A strong irritant that may cause burns to skin and eyes; Inhalation may cause liver and kidney injury; [CHRIS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion, inhalation, and skin absorption; [Sigma-Aldrich MSDS] See "CHLOROPHENOLS."
Biomedical References
Exposure Assessment
Vapor Pressure
2.53 mm Hg
Odor Threshold Low
0.0036 ppm
Lethal Concentration
LC50 (rat) = 390 ppm/4hr
Explanatory Notes
Flash point = 64 deg C; [ICSC] Odor threshold (threshold concentration) from CHEMINFO; The Guide in the Emergency Response Guidebook is for "Chlorophenols, liquid" VP from ChemIDplus;
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: