Oxybenzone
Agent Name
Oxybenzone
CAS Number
131-57-7
Formula
C14-H12-O3
Major Category
Other Uses
Synonyms
(2-Hydroxy-4-methoxyphenyl)phenylmethanone; 2-Hydroxy-4-methoxybenzophenone; 4-Methoxy-2-hydroxybenzophenone; Advastab 45; Anuvex; Benzophenone, 2-hydroxy-4-methoxy-; Benzophenone-3; Chimassorb 90; Cyasorb UV 9; Cyasorb UV 9 Light Absorber; Escalol 567; HMBP; MOB; MOD; Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-; Ongrostab HMB; Oxibenzona [INN-Spanish]; Oxibenzonum; Oxybenzon; Oxybenzonum [INN-Latin]; Spectra-sorb UV 9; Sunscreen UV-15; Syntase 62; UF 3; UV 9; Uvinul 9; Uvinul M40; Uvistat 24; [ChemIDplus]
Category
Sunscreens
Description
Colorless solid; [Hawley] Pale yellow powder; [MSDSonline]
Sources/Uses
Used as an ultraviolet light absorber and stabilizer (especially in plastics), photostabilizer for synthetic resins, and topical sunscreen agent; [HSDB]
Comments
Of 7 sunscreen allergens photo-patch tested in 1990 in 355 Swedish patients, it caused the most positive reactions (15 photocontact and 1 contact); [HSDB] May cause contact dermatitis, urticaria, and irritation; [CAMEO] It is tested in a 3% concentration in petrolatum; It causes both contact and photo-contact allergic reactions; Patients may also be allergic to other benzophenone sunscreens; [Marks, p. 221] An irritant; Effects in high-dose animal studies include effects on liver, kidneys, and reproductive system; Oral LD50 (rat) = 7500 mg/kg; [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
1.42E-06 mm Hg
Adverse Effects
Skin Sensitizer
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
PACD (photoallergic contact dermatitis)
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: