2-Vinylpyridine

Synonyms

2-Ethenylpyridine; 2VP; Pyridine, 2-ethenyl-; Pyridine, 2-vinyl-; alpha-Vinylpyridine; [ChemIDplus] UN3073

Category

Pyridines

Description

Colorless liquid with an unpleasant odor; [HSDB]

Sources/Uses

Used as an acrylic fiber comonomer, grafting reagent (ashless lubricant dispersants), and chemical intermediate; [HSDB]

Comments

A skin, eye, nose, and mucous membrane irritant; May cause skin burns and sensitization; Emergency treatment: "Pyridine"; Pyridine is an irritant that causes CNS depression after ingestion of 1/2 cup or inhalation of 6-12 ppm; It can cause liver and kidney injury; [HSDB] May cause delayed burns to skin; A severe eye and respiratory tract irritant; May cause skin sensitization; [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; May be absorbed through skin; [Alfa Aesar MSDS] May cause burns; Toxic if swallowed; Harmful if inhaled; May cause allergic skin reactions; [Aldrich MSDS] Vinylpyridines, stabilized (UN3073) has warning of explosive polymerization; [ERG 2016] See "Pyridine."

Reference Link #1

Biomedical References

0.3 ppm

Odor Threshold High

0.5 ppm

LC50 (rat) = 610 mg/m3

Yes

Explanatory Notes

VP = 10 mm Hg at 44.5 deg C; [HSDB] Odor threshold form HSDB; The Guide in the Flash point = 42 deg C; [ICSC] Emergency Response Guidebook is for "Vinylpyridines, stabilized."

Yes

Yes

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic