3,3',4,4'-Tetrachlorobiphenyl

Synonyms

1,1'-Biphenyl, 3,3',4,4'-tetrachloro-; 3,3',4,4'-Tetrachloro-1,1'-biphenyl; 3,4,3',4'-Tetra coplanar polychlorinated biphenyl; 3,4,3',4'-Tetrachlorobiphenyl; 4-CB; Biphenyl, 3,3',4,4'-tetrachloro-; PCB 77; [ChemIDplus] UN2315

Category

Halogenated Polyaromatics

Description

White solid; [MSDSonline]

Sources/Uses

Found in commercial PCB’s, their manufacturing facilities, and during destruction or degradation of products containing PCB’s; [HSDB]

Comments

Emergency medical treatment: see PCB-PBB; A skin and eye irritant; Evidence of reproductive and developmental toxicity; Effects in feeding study with Rhesus monkeys at 0.3-3.0 ppm include chloracne, sebaceous gland atrophy, involution of the thymus, and hyperplasia of gastric mucosa; [HSDB] See "Chlorodiphenyl (42% chlorine). See "Polychlorinated biphenyls" and linked occupational disease.

PCB's not commercially produced in the US since 1977; [HSDB]

Biomedical References

1.64E-05 mm Hg

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Polychlorinated biphenyls."

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Chloracne

Established

Anticipated human carcinogen

Diseases

Occupational diseases associated with exposure to this agent:

• Chloracne