4,4'-Diacetylbenzidine

Agent Name
4,4'-Diacetylbenzidine
CAS Number
613-35-4
Formula
C16-H16-N2-O2
Major Category
Nitrogen Compounds
4,4'-Diacetylbenzidine formula graphical representation
Synonyms
4',4'''-Biacetanilide; 4,4'-Diacetamidobiphenyl; 4,4'-Diacetylaminobiphenyl; Acetamide, N,N'-(1,1'-biphenyl)-4,4'-diylbis-; Acetamide, N,N'-4,4'-biphenylylenebis-; Benzidine, N,N'-diacetyl-; Biphenyl, 4,4'-diacetamido-; Diacetylbenzidine; N,N'-(1,1'-Biphenyl)-4,4'-diylbis-acetamide; N,N'-4,4'-Biphenylylenebisacetamide; N,N'-Diacetyl benzidine; N,N'-Diacetylbenzidine; [ChemIDplus]
Category
Benzidine and Derivatives
Description
White solid; [HSDB] Pale yellow powder; [TCI MSDS]
Sources/Uses
Used as a research chemical and to prepare 3,3'-Dichlorobenzidine and 3,3'-Dinitrobenzidine; [HSDB]
Comments
May irritate eyes and respiratory tract; May cause methemoglobinemia, anemia, and kidney injury; [ICSC] Glomerular lesions in feeding study of rats developed within a few months; IP injection in rats causes hepatocellular degeneration and changes in bile canaliculi; Evidence of carcinogenicity and mutagenicity in experimental animals; Emergency treatment: Methemoglobinemia; [HSDB] See "Benzidine."
Biomedical References

Adverse Effects

Methemoglobinemia
MetHgb is secondary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Possible (2b)

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.