p-tert-Butyltoluene

Synonyms

1-Methyl-4-tert-butylbenzene; 1-tert-Butyl-4-methylbenzene; 4-Methyl-tert-butylbenzene; 4-tert-Butyl-1-methylbenzene; 4-tert-Butyltoluene; 8-Methylparacymene; Benzene, 1-(1,1-dimethylethyl)-4-methyl-; PTBT; TBT; Toluene, p-tert-butyl-; p-Methyl-tert-butylbenzene; p-TBT; p-t-Butyltoluene; p-tert-Butyltoluene; [ChemIDplus] UN2667

Category

Aromatic Solvents

Description

Colorless liquid with a distinct aromatic odor; somewhat like gasoline; [NIOSH]

Sources/Uses

Used as solvent for resins and as a chemical intermediate for the chemical and pharmaceutical industries; [HSDB]

Comments

Liver injury occurs in chronic inhalation studies of experimental animals. Giddiness was observed in volunteers exposed at 160 ppm. [ACGIH] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations can cause CNS depression; [ICSC]

Reference Link #1

Biomedical References

Insufficient data

1 ppm

10 ppm

100 ppm

Excerpts from Documentation for IDLHs

Basis for original (SCP) IDLH: The chosen IDLH is based on the female rat 1­hour LC50 of 934 ppm reported by Hine et al. [1954]. . . . Human data: Giddiness and altered respiration have been reported in volunteers exposed to 160 ppm for 15 minutes [Hine et al. 1954].

0.65 mm Hg

5 ppm

360 ppm

LC50 (rat) = 165 ppm/8H

Explanatory Notes

Odor threshold (recognition) from CHEMINFO; Flash point = 136 deg F; VP from HSDB;

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing