4-Picoline
Agent Name
4-Picoline
CAS Number
108-89-4
Formula
C6-H7-N
Major Category
Nitrogen Compounds
Synonyms
4-Methylpyridine; Ba 35846; Pyridine, 4-methyl-; gamma-Methylpyridine; gamma-Picoline; p-Methylpyridine; p-Picoline; [ChemIDplus] UN2313
Category
Pyridines
Description
Colorless liquid with an obnoxious, sweetish odor; [HSDB]
Sources/Uses
Used as a chemical intermediate, solvent (pharmaceuticals, resins, dyestuffs, rubber accelerators, pesticides, and waterproofing agents), laboratory reagent, catalyst, and curing agent; [HSDB] Picolines are constituents in cigarette smoke, bone oil, coal tar, and coke oven emissions. [AIHA]
Comments
A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation of high concentrations can cause unconsciousness; The liquid defats the skin; [ICSC] An irritant; Can be absorbed through skin; [MSDSonline] An irritant that can cause CNS depression; Liver changes occur in rats exposed to chronic high doses; [AIHA] See "Pyridine."
Biomedical References
Exposure Assessment
Vapor Pressure
5.77 mm Hg
Lethal Concentration
LCLo (rat) = 1,000 ppm/4h
Explanatory Notes
Flash point = 57 deg C; [ICSC] The Guide in the Emergency Response Guidebook is for "Picolines." VP from ChemIDplus;
WEEL
2 ppm, STEL = 5 ppm
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.