Captafol

Agent Name
Captafol
Alternative Name
Difolatan
CAS Number
2425-06-1
Formula
C10-H9-Cl4-N-O2-S
Major Category
Pesticides
Captafol formula graphical representation
Synonyms
Captofol; N-((1,1,2,2-Tetrachloroethyl)thio)-4-cyclohexene-1,2-dicarboximde; Crisfolatan; Difosan; Folcid; Haipen; Kenofol; Merpafol; Pillartan; Sanseal; Santar-SM; Sanspor; Difolatan
Category
Fungicides
Description
White, crystalline solid with a slight, characteristic pungent odor. [fungicide] [Note: Available commercially as a wettable powder or in liquid form.] [NIOSH]
Sources/Uses
The thiophthalimides are widely used fungicides on seeds, field crops, and stored produce; [EPA Pesticides] Used as an agricultural fungicide in large quantities worldwide; Limited industrial use in paints and plastics; [ACGIH]
Comments
The thiophthalimides include captan, captafol, and folpet; no systemic poisonings in humans have been reported; [EPA Pesticides] Allergic contact dermatitis in pesticide handlers is most likely due to maneb, carbofuran, carbaryl, captan, folpet, or captafol. [Marks, p. 312] TLV Basis is liver damage, kidney damage and dermal sensitization; A potential respiratory sensitizer; [ACGIH]
Restricted
Captafol is no longer registered in the U.S. [EPA Pesticides]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.1 mg/m3, inhalable fraction and vapor
Vapor Pressure
8E-09 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
IARC Carcinogen
Probable (2a)
NTP Carcinogen
Anticipated human carcinogen
ACGIH Carcinogen
Confirmed Animal

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: