Acetyl tributyl citrate
Agent Name
Acetyl tributyl citrate
CAS Number
77-90-7
Formula
C20-H34-O8
Major Category
Other Classes
Synonyms
1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester; 2-(Acetyloxy)-1,2,3-propanetricarboxylic acid, tributyl ester; 2-Acetyltributylcitrate; 2-Acetoxy-1,2,3-propanetricarboxylic acid tributyl ester; Acetyl tributyl citrate; Acetylcitric acid, tributyl ester; Blo-trol; Citric acid, tributyl ester, acetate; Citroflex A; Citroflex A 4; Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylate; Tributyl 2-acetoxy-1,2,3-propanetricarboxylate; Tributyl O-acetylcitrate; Tributyl acetyl citrate; Tributyl acetylcitrate; Tributyl citrate acetate; [ChemIDplus]
Category
Esters, Other
Description
Colorless liquid with a mild sweet odor; [HSDB]
Sources/Uses
Used as a flavoring agent and plasticizer for vinyl resins, rubber, and cellulosic resins; Also used to make resinous and polymeric coatings and paper/paperboard for use in contact with food; [HSDB]
Comments
Emergency treatment: "Irritants"; No observations of skin irritation or sensitization in study with 59 volunteers; Intravenous dosing of cats and rabbits caused dose-related drop in blood pressure (found to be caused by cardiac inhibition); Other effects noted in high-dose animal studies by different exposure routes include decreased weight gain, decreased hemoglobin (no indication of aplastic anemia in bone marrow smears), and neurological effects (i.e. local anesthesia and blockage of neural transmission); No evidence of mutagenicity and limited evidence of cytotoxicity; [HSDB] Causes somnolence in lethal-dose feeding studies of rats; [RTECS] Safe to use as a flavoring agent in food; [JECFA]
Biomedical References
Exposure Assessment
Vapor Pressure
4.55E-06 mm Hg
Explanatory Notes
Flash point = 204 deg C; [Hawley]
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Processes
Industrial Processes with risk of exposure: