3-Nitropropionic acid
Agent Name
3-Nitropropionic acid
CAS Number
504-88-1
Formula
C3-H5-N-O4
Major Category
Biological Agents
Synonyms
3-Nitropropanoic acid; BNP; Bovinocidin; Hiptagenic acid; NITROPROPIONIC ACID, BETA; Propanoic acid, 3-nitro-; Propionic acid, 3-nitro-; beta-Nitropropionic acid; [ChemIDplus] UN2811
Category
Mycotoxins
Description
Golden solid; [CAMEO] Fine faintly beige crystals; [MSDSonline]
Sources/Uses
A naturally occurring mycotoxin that is associated with motor disorders in livestock and humans that have ingested contaminated food; Used as a research chemical; Not commercially produced in the US; [HSDB]
Comments
Emergency treatment: Methemoglobinemia; Thought to be the cause of acute mildewed sugar cane poisoning; There were 88 deaths in China attributed to this mycotoxin between 1972 and 1989; [HSDB] Causes somnolence and seizures in intraperitoneal, lethal-dose studies of rats; LDLo (rabbits) = 355 mg/kg; Has effect on neurotransmitters (putative); [RTECS] A skin, eye, mucous membrane, and upper respiratory tract irritant; [CAMEO] An irritant; [MSDSonline]
Biomedical References
Exposure Assessment
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."
Adverse Effects
Methemoglobinemia
MetHgb is secondary toxic effect
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.