4-Hydroxybenzoic acid
Agent Name
4-Hydroxybenzoic acid
CAS Number
99-96-7
Formula
C7-H6-O3
Major Category
Other Classes
Synonyms
4-Carboxyphenol; 4-Hydroxybenzoesaeure; Acido p-idrossibenzoico [Italian]; Kyselina 4-hydroxybenzoova [Czech]; p-Hydroxybenzoic acid; p-Oxybenzoesaure [German]; p-Salicylic acid; Benzoic acid, 4-hydroxy-; Benzoic acid, p-hydroxy-; [ChemIDplus]
Category
Benzoic Acid Derivatives
Description
Colorless solid; [Hawley] White powder; [MSDSonline]
Sources/Uses
Used as an intermediate for dyes, fungicides, cosmetics, and drugs; as a food preservative, corrosion inhibitor, anti-oxidant, and emulsifier; as a component in the manufacture of polyester; and as a constituent of liquid crystal polymers; [HSDB] Used as an intermediate for pesticides, antiseptics, and pharmaceuticals; [eChemPortal: SIDSUNEP]
Comments
A mild skin irritant and sensitizer; A moderate eye irritant; [eChemPortal: SIDSUNEP] In animal experiments, causes somnolence, ataxia and changes to liver and kidneys; [RTECS] Oral LD50 (mouse) = 2200 mg/kg; [Sax] Safe when used as a flavoring agent; [JECFA] An irritant; Effects in high-dose animal studies include acute tubular necrosis); [MSDSonline]
Biomedical References
Exposure Assessment
Vapor Pressure
1.9E-07 mm Hg
WEEL
5 mg/m3
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.