p-Aminosalicylic acid
Agent Name
p-Aminosalicylic acid
CAS Number
65-49-6
Formula
C7-H7-N-O3
Major Category
Nitrogen Compounds
Synonyms
2-Hydroxy-4-aminobenzoic acid; 3-Hydroxy-4-carboxyaniline; 4-Amino-2-hydroxybenzoic acid; 4-Aminosalicylic acid; A 1909; APAS; Aminopar; Aminosalicylic acid; Aminosalyl; Aminox; Apacil; Benzoic acid, 4-amino-2-hydroxy-; Deapasil; Entepas; Ferrosan; Gabbropas; Helipidyl; Hellipidyl; Kyselina p-aminosalicylova [Czech]; NIH 2939; Osacyl; PAS; PAS (VAN); PAS (acid); PAS-C; Pamacyl; Pamisyl; Para-Pas; Para-amino salicylic acid; Paramycin; Parasal; Parasalicil; Parasalindon; Pas; Pasa; Pasalon; Pasara; Pascorbic; Pasdium; Pasem; Paser; Paser Granules; Pask; Pasmed; Pasnodia; Pasolac; Propasa; Rezipas; Salicylic acid, 4-amino-; Sanipirol-4; [ChemIDplus]
Category
Aminobenzoic Acids
Description
White or nearly white solid; Affected by light and air; [Hawley] Beige powder; [MSDSonline]
Sources/Uses
Used as an industrial preservative, a chemical intermediate, and an antitubercular drug; [HSDB]
Comments
Not expected to increase congenital malformations based on animal studies; [REPROTOX] Oral LD50 (mouse) = 4000 mg/kg; [RTECS] An eye irritant; Targets the GI system and liver; [MSDSonline] See "p-Aminosalicylic acid sodium salt dihydrate."
Biomedical References
Exposure Assessment
Vapor Pressure
4E-06 mm Hg
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.