Amanin

Synonyms

9,18- (Iminoethaniminoethaniminoethaniminomethano)pyrrolo(1',2':8, 9)(1,5,8,11,14)thiatetraaza cyclooctadecino(18,17-b)indole- 6-acetic acid, 1,2,3,5,6,7,8,9,10,12,17,18,19,20,21,22,23,23a-octadecahydro-29-sec-butyl-21-(2,3-dihydroxy-1-methylpropyl)-2-hydroxy-5,8,20,23,24,27,30,33-octaoxo-, 11-oxide; Amanine; alpha-Amanitin, 1-L-aspartic acid-4-(2-mercapto-L-tryptophan)-; [ChemIDplus]

Category

Mushroom Toxins

Sources/Uses

Amanitin toxins from the poisonous Amanita phalloides mushroom include amanin. [Merck Index]

Comments

Inhibits protein synthesis in mammalian cells; [Merck Index] Emergency treatment: "Mushrooms- cyclopeptides"; [HSDB] Oral LD50 (mammal) = 0.5 mg/kg; [RTECS] See "alpha-Amanitin" and "beta-Amanitin."

Reference Link #1

Biomedical References

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Information

No other related information on this agent was found.