Amiton
Agent Name
Amiton
Alternative Name
Tetram
CAS Number
78-53-5
Formula
C10-H24-N-O3-P-S
Major Category
Pesticides
Synonyms
Tetram; (2-Diethylamino)ethylphosphorothioic acid O,O-diethyl ester; Amiton [BSI]; Chipman 6200; DSDP; Diethyl S-2-diethylaminoethyl phosphorothioate; Inferno; Metram; Metramac; O,O-Diethyl S-(2-diethylaminoethyl) thiophosphate; O,O-Diethyl S-2-diethylaminoethyl phosphorothioate; O,O-Diethyl S-2-diethylaminoethyl phosphorothiolate; O,O-Diethyl S-diethylaminoethyl phosphorothiolate; O,O-Diethyl-S-(beta-diethylamino)ethyl phosphorothioate; O,O-Diethyl-S-2-(diethylamino)ethylester kyseliny thiofosforecne [Czech]; Phosphorothioic acid, S-(2-(diethylamino)ethyl) O,O-diethyl ester; R-5,158; Rhodia-6200; S-(2-(Diethylamino)ethyl) O,O-diethylphosphorothioate; S-(2-(Diethylamino)ethyl)phosphorothioic acid O,O-diethyl ester; S-(Diethylaminoethyl) O,O-diethyl phosphorothioate; VG; [ChemIDplus]
Category
Organophosphate Insecticides
Description
Colorless liquid; [HSDB]
Sources/Uses
Used as contact insecticide, miticide, and acaricide; [HSDB]
Comments
"One of the most toxic of the organic phosphorus insecticides." [HSDB] A highly toxic cholinesterase inhibitor; [CAMEO] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Explanatory Notes
VP = 0.01 mm Hg at 80 deg C; [HSDB]
Adverse Effects
Other Poison
Organophosphate
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: