Azadirachtin
Agent Name
Azadirachtin
CAS Number
11141-17-6
Formula
C35-H44-O16
Major Category
Pesticides
Synonyms
Azadirachtin A; Azadirachtin-A; Bioneem; NeemAzal; [ChemIDplus]
Category
Other Insecticides
Description
Yellow-green solid; [HSDB]
Sources/Uses
A tetranortriterpinoid isolated from different plants; Insect feeding deterrent; [Merck Index] Used as an insecticide; Registered for use in the US; [HSDB] Derived from the neem tree indigenous to India and Burma; Also has nematicidal and antifungal effects; [Krieger, p. 147]
Comments
Toxic by ingestion--causes seizures and coma; [HSDB] Commercial neem formulations may contain other liminoids; Insecticidal effects are probable due to interference with several cellular processes; In animal experiments, causes neurotoxicity and reversible reproductive toxicity; Causes mild irritation and is a dermal sensitizer; In human case reports, encephalopathy develops within hours of ingesting 5-10 ml of neem seed oil; [Krieger, p. 147-54]
Biomedical References
Exposure Assessment
Explanatory Notes
Flash point > 58 deg C; [HSDB]
Adverse Effects
Skin Sensitizer
Yes
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: