Azinphos-ethyl

Synonyms

3,4-Dihydro-4-oxo-3-benzotriazinylmethyl O,O-diethyl phosphorodithioate; 3-Diethoxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one; 3-Diethyloxyphosphinothioylthiomethyl-1,2,3-benzotriazin-4(3H)-one; Athyl-gusathion; Azinfos-ethyl [Dutch]; Azinophos-ethyl; Azinos; Azinphos-aethyl [German]; Azinphos-ethyl; Azinphos-etile [Italian]; Azinugec E; BAY 16255; BAY 16259; Bayer 16259; Benzotriazine derivative of an ethyl dithiophosphate; Bionex; Cotnion-ethyl; Crysthion; ENT 22,014; Ethyl Gusathion; Ethyl azinphos; Ethyl guthion; Ethyl homolog of guthion; Gusathion; Gusathion A; Gusathion A-M; Gusathion H; Gusathion H and K; Gusathion K; Gusathion K forte; Gusation A; Gutex; Guthion (ethyl); O,O-Diaethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiophosphat [German]; O,O-Diaethyl-S-(4-oxobenzotriazin-3-methyl)-dithiophosphat [German]; O,O-Diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate (9CI); O,O-Diethyl S-(4-oxobenzotriazino-3-methyl)phosphorodithioate; O,O-Diethyl S-(4-oxobenzyltriazine-3-methyl) dithiophosphate; O,O-Diethyl phosphorodithioate S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one; O,O-Diethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithio fosfaat [Dutch]; O,O-Diethyl-S-((4-oxo-3H-1,2,3-benzotriazin-3-yl)-methyl)-dithiofosfaat [Dutch]; O,O-Diethyl-S-(4-oxo-3H-1,2,3-benzotriazine-3-yl)-methyl-dithiophosphate; O,O-Dietil-S-((4-oxo-3H-1,2,3-benzotriazin-3-il)-metil)-ditiofosfato [Italian]; Phosphorodithioic acid, O,O-diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) ester; Phosphorodithioic acid, O,O-diethyl ester, S-ester with 3-(mercaptomethyl)-1,2,3-benzotriazin-4(3H)-one; R 1513; S-(3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-diethyl phosphorodithioate; S-3,4-Dihydro-4-oxobenzo(d)(1.2.3)triazin-3-ylmethyl O,O-diethyl phosphorodithioate; Sepizin L; Triazotion [Russian]; [ChemIDplus] UN2783

Category

Organophosphate Insecticides

Description

Colorless solid; [HSDB] Colorless crystalline solid; [MSDSonline]

Sources/Uses

Used as a non-systemic insecticide and acaricide to protect fruits, vegetables, cotton, tobacco, ornamentals, other crops, and forestry; [HSDB]

Comments

Effects in high dose animal studies include depression of cholinesterase activity; [HSDB] Extremely toxic cholinesterase inhibitor that may cause death as a result of minor exposure to small amounts; [CAMEO] Toxic by ingestion, skin absorption, or inhalation; [INCHEM PDS: Azinphos-ethyl - 1994] May cause irritation; Effects in high dose animal studies include convulsions; [MSDSonline] “The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline.” [TLVs and BEIs]

No longer used or produced in the US or Canada (high toxicicity); [HSDB]

Biomedical References

Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

2.4E-06 mm Hg

LC50 (rat) = 390 mg/m3

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Organophosphorus pesticide, solid, toxic."

Other Poison

Organophosphate

Diseases

Occupational diseases associated with exposure to this agent:

• Organophosphates & carbamates, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)