Estragole

Synonyms

1-Methoxy-4-(2-propenyl)benzene; 1-Allyl-4-methoxybenzene; 1-Methoxy-4-(2-propen-1-yl)benzene; 3-(p-Methoxyphenyl)propene; 4-Allyl-1-methoxybenzene; 4-Allylanisole; 4-Allylmethoxybenzene; 4-Methoxyallylbenzene; Allylphenyl methyl ether, p-; Anisole, p-allyl-; Benzene, 1-methoxy-4-(2-propenyl)-; Chavicol methyl ether; Chavicol, O-methyl-; Chavicyl methyl ether; Esdragol; Esdragole; Esdragon; Estragole (natural); Isoanethole; Methyl chavicol; Tarragon; Terragon; p-Allylanisole; p-Allylmethoxybenzene; p-Methoxyallylbenzene; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Colorless liquid with an odor of anise; [Hawley]

Sources/Uses

Naturally occurs in tarragon oil, basil oils, anise bark oil, and others; [Hawley] Used as a flavoring ingredient and a fragrance in perfumes and soaps; [HSDB]

Comments

Emergency treatment: "Essential oils"; Essential oils can cause CNS depression and aspiration pneumonia after ingestion; Commercial products of essential oils usually contain concentrations of 1% to 20%, and a potentially toxic exposure is 5-15 mL; No sensitization when tested at 3% in petrolatum on 25 volunteers; Minor liver damage found in rats fed 605 mg/kg/day for four days; [HSDB] Moderate irritant on rabbit skin; Causes somnolence and coma at lethal doses in rats; [RTECS];

Biomedical References

0.05 mm Hg

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect